i use Reason 4 and love it

rewired to Pro Tools LE 6.4

Lmao i will be upgrading to Pro Tools LE 8 very soon.
Also Propellerheads are launching there new program soon "Record" you can use that together with Reason. Might wanna check it out.
But in the end of the day its all about your knowledge of structureing/arranging a track that will shine through. Programs are all the same just different GUI's, which wun you feel comftorble with & get your work done faster go for that one.
www.myspace.com/15thsine
www.myspace.com/revampedproductions